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韩珉教授

更新:2006-6-14 来源:复旦大学 作者:韩珉 【
d Han, M. (1999) A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting. Development. 126 (3), 597-606. Abstract
Malone, C. J., Fixen, W. D., Horvits, H. R. and Han, M. (1999) UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development. Development. 126, 3171-3181.
Kniazeva, M., Zawistovski, J., Han, M. (1998). Addition of a second primer in PCR mixture after the first step of initial denaturation greatly improves synthesis of specific PCR fragments. TTO#1416, Elsevier Trends Journals, 1998.
Zhang K, Garibaldi DC, Kniazeva M, Albini T, Chiang MF, Kerrigan M, Sunness JS, Han M, Allikmets R. (1999). A novel mutation in the ABCR gene in four patients with autosomal recessive Stargardt disease. Am J Ophthalmol. 128:720-4
Kniazeva, M., Chiang, M. F., Cutting, G. R.,  Han, M., Zhang, K. (1999) Clinical and genetic studies of an autosomal dominant cone-rod dystrophy with features of Stargardts disease. Ophthalmic Genetics 20, 71-81. Abstract
Kniazeva, M., Chiang, M. F., Han, M., Zhang, K. (1999)  A new gene forautosomal dominant Stargardt-like disease maps to chromosome 4. Amer. J. Hum. Gen. 64, 1394-1399.
Zhang K, Kniazeva M, Han M., Dean M, Allikmets R.  The ABCR Gene in Recessive and Dominant Stargardt Disease: A genetic Pathway in Macular Degeneration.  Genomics, 60(2):234-237, 1999.


2000

Kniazeva M, Traboulsi EI, Yu Z, Stefko ST, Gorin MB, Shugart YY, O'Connell JR, Blaschak CJ, Cutting G, Han M, Zhang K. (2000). A new locus for dominant drusen and macular degeneration maps to chromosome 6q14. Am J Ophthalmol.  130:197-202.

Stewart, S., Sundaram, M., Zhang, Y., Lee, J., Xiong, Y. Han, M., and Guan, K-L. (1999). Kinase Suppressor of Ras (KSR) forms a multi-protein signaling complex and modulates MEK localization. MCB, 19, 5523-5534.
Li, W., Han, M. and Guan, K.L. (2000).  The Leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf.  Gen & Dev.14, 895-900.

Fay, D.S. and Han, M. (2000). The Synthetic Multivulval Genes of C. elegans: Functional redundancy, Ras-antagonism, and cell fate determination. Genesis.  26, 279-284.

Grant, K, Hanna-Rose, W. and Han, M. (2000). Sem-4 promotes Caenorhabditis elegans vulval  fate determination through regulation of lin-39 hox. Devel. Biol.  224, 496-506.

Han, M. (2000). Studies on Ras-mediated signal transduction in C. elegans. In Sterm Cells and Development. Ed. By Jinseng Ye, Tian Xu, Tang Xifang and Bei
Haitial.  Medical Science Press. Beijing, China.

Chen, Z. and Han, M.(2000). Building a protein interaction map:research in the post-genomic era. BioEssays,22, 503-6.

Hanna-Rose, W. and Han, M. (2000). Getting your signal crossed. Curr. Opin. in Dev. Genetics. 10, 523-528.

Fay, D. S. and Han, M. (2000). Mutations in the C. elegans cyclin E gene reveal a timing mechanism that controls vulval cell differentiation. Development, 18,4049-4060.

2001

Zhang K, Kniazeva M, Han M, Li W, Yu Z, Yang Z, Li Y, Metzker ML, Allikmets R, Zack DJ, Kakuk, LE, Lagali PS, Wong PW, MacDonald IM, Sieving PA,
Figueroa DJ, Austin CP, Gould RJ, Ayyagari R, Petrukhin K.  (2001). A 5bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy. Nature Genetics, 27, 89-93.

Yoder, J. and Han, M. (2001).  Cytoplasmic dynein light intermediate is required for discrete aspects of mitosis in Caenorhabditis elegans.  Mol. Cell. Biol  12, 2921-2933.

Chen, Z., Han, M. (2001)  Role of C. elegans lin-40 MTA in vulval fate specification and morphogenesis. Development. 128, 4911-4921.

Starr, D, Hermann, GJ., Malone, C. Fixsen, W., Priess, J. Horvitz, HR and Han, M. (2001). unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration. Development.  128, 5039-5050.

Chen, Z. and Han, M. (2001). Role of Rb/E2F, the NuRD Complex, and Ras in Regulating a lin-39 Hox-mediated Cell Fusion Process during Vulval Fate Specification in C. elegans Curr. Biol. 11, 1874-1879.

Spencer, A., Orita, S., Malone, C., and Han, M. (2001) A RHO GTPase mediated pathway is required during P cell migration in C. elegans. Proc. Natl. Acd. Sci.  USA. 98, 13132-13137.


2002

Hanna-Rose, W. and Han, M. (2002). The Caenorhabditis elegans EGL-26 protein mediates vulval cell morphogenesis.  Devel. Bio. 24, 247-258. (Cover illustration)

Antoshechkin, I. and Han, M. (2002). Caenorhabditis elegans evl-20 gene encodes a functional homologue of human small GTPase ARL2 and regulates cytoskeleton dynamics during cytokinesis and morphogenesis. Developmental Cell, 2, 579-591.

Starr, D. and Han, M. Role of ANC-1 in Tethering Nuclei to the Actin Cytoskeleton. Science. 298, 406-409.

Suzuki, Y., Morris, G., Han, M. and Wood, W.B. (2002). A cuticle collagen encoded by the lon-3 gene may be a target of TGF-beta signaling in determining Caenorhabditis elegans body shape. Genetics, in press.

Fay, D., Keneen, S. and Han, M. (2002)  fzr-1 and lin-35/Rb Function Redundantly to Control Cell Proliferation in C. elegans as Revealed by
Nonbiased Synthetic Screen. Genes & Dev. 16. 503-517. (Cover illustration)


2003

Fay D., Large, E. Han, M. and Darland, M. (2003) lin-35/Rb and ubc-18, an E2 ubiquitin-conjugating enzyme, function redundantly to control
pharyngeal morphogenesis in C. elegans  Development.130, 3319-3330.

Kniazeva, M., Sieber, M. McCauley. S. Zhang, K. Watts, J., Han, M. (2003). Suppression of C. elegans ELO-2 function results in disruption of

palmitic acid elongation and causes multiple physiological defects including abnormal ultradian rhythms. Genetics, 163 159-169.

Starr, D and Han, M. (2003) ANChors away: an actin based mechanism of nuclear positioning. Journal of Cell Science. 15;116:211-6.

Cui, M. and Han. M. (2003) Cis Regulatory Requirements for Vulval Cell-Specific Expression of the Caenorhabditis elegans  Fibroblast Growth Factor
Gene egl-17. Dev. Biol.  257, 104-116.

Wang, F., Yoder, J., Antoshechkin, I, and Han, M. (2003). C. elegans EVL-14/PDS-5 and SCC-3 are essential for sister chromatid cohesion in mitosis and
meiosis. MCB, 23, 7698-7707.



2004

Yoder, J.H., Chong, H., Guan, K.L, and Han, M. (2004). Modulation of KSR activity in C . elegans by Zn ions, PAR-1 kinase and PP2A phosphatase, EMBO J. 23, 111-119.
Eastburn, D. and Han, M. (2004). When Ras Signaling Reaches the Mediator (2004). Developmental Cell. 6 158-159.
Eastburn, D. and Han, M. (2004). Ras signaling in C. elegans.  A book chapter.  In press.
Bourbon HM and 44 other authors (2004). A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.  Mol Cell 14(5):553-557, 2004. Cui, M., Fay DS and Han, M. (2004). lin-35/Rb cooperates with the SWI/SNF complex to control Caenorhabditis elegans Larval Development.  Genetics,  167, 1177-85 Kniazeva, M. Crawford, QT, Seiber, M., Wang, C-Y and Han, M. (2004). Mono Methyl Branched Fatty Acids play essential role in C. elegans development. PLoS Biology, 2 (9),: e257. Chen, Z. Eastburn, D. and Han, M. (2004). C. elegans nuclear receptor nhr-25, regulates epidermal cell development.  MCB, 24, 7345-7358 (Cover photo).
  Li, W. Lee, J. Vikis, HG., Hoshino, A. Liu, G., Aurandts, J. Jiang, H., Fearon, ER., Han, M., Rao, Y., Hong, K., and Guan, K-L. (2004) Activation of FAK and Src are receptor proximal events required for netrin signaling. Nature Neuroscience, 7, 1213-1221.
2005

*Grady, RM., *Starr, D, Ackerman, G. Sanes, JR., and Han, M. (2005). Syne proteins anchor muscle nuclei at the neuromuscular junction. PNAS,  102, 4359-64. (*co-first authors) (with mini-review).

Del Campo, JJ., Opoku-Serebuoh, E. Issacson, AB., Tucker, M., Han, M. and Mohler WA. (2005) A single-protein fusogen in the somatic cells of C. elegans.  Current Biology, 15, 413-23. Zhu, H. ,Xu, T. Han, M., Zhuang, Y. and Wu, X. (2005) Ubiquitous expression of mRFP1 in transgenic mice. Genesis. 2:86-90. Starr, DA and Han, M. (2005). A genetic approach to study the role of nuclear envelope components in nuclear positioning.  Novartis Found Symp. 264, 208-219. Ding, S., Wu, X., LI, G., Han, M., Zhuang, Y., and Xu, T (2005). Efficient Transition of PB transposon in mammalian cells and mice. Cell 122, 473-483. (Cover, featured article of the issue, Mini-review).  Ding, L., Spencer, A., Morita, K. and Han, M. (2005). The developmental timing regulator AIN-1 interacts with argonaute protein ALG-1, miRISCs and may target ALG-1 to cytoplasmic P bodies in C. elegans.  Mol. Cell. 19, 437-447 (featured article of the issue, Minireview in Dev Cell). Tucker, M., Sieburt M. Morphew M. and Han, M. (2005). The Caenorhabditis elegans aristaless orthologue, arl-1, is required for maintaining the functional and structural integrity of the amphid sensor organs. MBC, 16:4695-704 (Epub 7/29/05). Eastburn and Han, M. (2005) A gain-of-function allele of cbp-1 leads to an increase in HAT activity and antagonism of activated Ras.  MCB, 25:9427-34.

Morita, K., Hirono, K. and Han, M. (2005) Th

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