CURRICULUM  VITAE

 

XIAO-HUI  ZHANG

 

CONTACT: Institute of Neuroscience, Shanghai Institutes for Biological Sciences   

                      Chinese Academy of Sciences, #234 SIBS Building

                      320 Yue-Yang Road, Shanghai 200031, China

 

E-MAIL: xhzhang@ion.ac.cn

 

ACADEMIC APPOINTMENT

12/2005 -    Co-principle Investigator, Laboratory of Neural Plasticity, Institute of Neuroscience, Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of sciences (CAS)

02/2003 – 12/2005   Associate Investigator, Laboratory of Neural Plasticity, Institute of Neuroscience, SIBS, CAS

 

EDUCATION

11/2000 – 01/2003  HFSP Postdoctoral Fellow, Department of Molecular and Cell Biology, University of California at Berkeley. USA.  Advisor: Dr. Mu-Ming Poo

08/1999 – 10/2000  Postdoctoral Fellow, Department of Biology, University of California at San Diego, USA. Advisor: Dr. Mu-Ming Poo

07/1999  Ph.D. in Neurobiology, Shanghai Institute of Physiology, CAS, China. Supervisor: Professor Pei-hong Zhu

07/1994   B. Sc in Biology, Hangzhou University, China

                         

AWARDS and HORNORS

2004 International Human Frontier Science Program (HFSP) Career Developing Award (CDA0019/2003-B)

2003 Chinese Academy of Sciences “Hundred Talents Program Award”

2000  International HFSP Long-term Fellowship (LTF)

1999 Chinese Academy of Science “Di-Ao” Scholarship, First Prize

1998  Director Scholarship of Shanghai Institute of Physiology, First Prize

 

RESEARCH GRANTS

2006-2009   Knowledge Innovation Program of the CAS - “Neural Mechanism Underlying the Visuo-auditory Learning and Memory” (Principle Investigator, KSCX2-YW-R-29)

2006-2011    Major State Basic Research Program of China – “Structural and Functional Plasticity of the Brain” (2006CB806600) –Section: Plasticity in Synaptic Transmission and Neuron-Glia Interaction”

2006-2008   Major State Basic Research Program of China – “Molecular Network for the Fate Determination of Stem Cells” (2006CB0F0900) – Section: Molecular Mechanisms Underlying Neuronal Differentiation and Brain Development. 

2004-2006 HFSP Career Developing Award – “Development and Plasticity of Retinotectal Synapses in vertebrate visual system in vivo” (CDA0019/2003-B)

2003-2006 Chinese Academy of Sciences “Hundred Talents Program Award”

 

TEACHING EXPERIENCE

2004 – present  SIBS Graduate Course in Neurobiology

                           2004-  “Learning & Memory: Cellular and Molecular Aspects”;

                           2006-  “Sleep, Dreaming and Emotional States”;

                           2004-2006 “Neural development: Refinement of synaptic connections”

 

PBULICATIONS (* corresponding author)

(1)  Xu C., Zhao M.X., Poo M.M.* and Zhang X.H.* GABAB receptor activation confers the frequency-dependent long-term potentiation of developing hippocampal GABAergic synapses. In preparation

(2)  Gao L.X., Liu C.H., Ye, C.Q., Dan Y., Poo M.M.* and Zhang X.H.* Short-term memory of stimuli interval in slow oscillation of auditory thalamic neurons. Submitted

(3)  Hao J., Wang X.D., Dan Y., Poo M.M.* and Zhang X.H.* A simple arithmetic rule for dendritic integration of excitatory and inhibitory inputs in pyramidal neurons. Submitted, under review by Nat. Neurosci.

(4)  Lu J.T., Li C.Y. Poo M.M.* and Zhang X.H.* (2007) Spike timing-dependent plasticity of neocortical excitatory synapses on inhibitory interneurons depends on target cell type. J. Neurosci. 27: 9711-9720.

(5)  Xu N.L., Ye C. Q., Poo M.M and Zhang X.H.* (2006) Coincidence detection of synaptic inputs is facilitated at the distal dendrites following LTP induction. J. Neurosci. 26: 3002–3009.

(6)  Wang X. D., Hao, J., Poo, M.M. and Zhang X.H.* (2006). Arithmetic rules of synaptic integration of excitation and inhibition. In: Advances in Neural Networks - ISNN 2006, vol. 3971 (Berlin, Heidelberg: Springer-Verlag Press), pp. 7-14.

(7)  Zhang X.H. and Poo M.M*. (2002) Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axon.  Neuron 36:675-688. (previewed by Dr.  A. K.  McAllister “Spatially Restricted Actions of BDNF” in the same issue)

(8)  Cheng X.Y., Chen K.Y., Zhang X.H. and Zhu P.H.* (2002) Effect of Zinc Ions on Caffeine-Induced Contracture in Vascular Smooth Muscle and Skeletal Muscle of Rat. Cell Physiol. Biochem..12:119-126.

(9)  Xia R.Y., Chen X.Y., Wang H., Chen X.Y., Wei Q.Q., Zhang X.H. and Zhu, P.H.* (2000) Biphasic modulation of ryanodine binding to sarcoplasmic reticulum vesicles of skeletal muscle by zinc ions.  Biochem. J. 345:279-286.

(10)          Zhang X.H., Wu J., Shen M.X., and Zhu P.H.* (1999) Calcium release induced by high K+ and caffeine in cultured skeletal muscle cells of embryonic chicken.  Pflugers Arch - Eur. J. Physiol. 438:827-836.

(11)          Zhang X.H., Sun J.H., and Zhu P.H.* (1999) Effect of phorbol esters on excitation-coupling and protein kinase C activity on frog twitch muscle fibers.  Pflugers Arch - Eur. J. Physiol. 438: 61-67.

(12)          Wu D., Zhang X.H. and Zhu P.H.* (1999) Effect of removal of external calcium on phosphoinositide hydrolysis in cultured myotubes of embryonic chicken.  Acta Physiol.Sinica.  51: 459-462.

(13)          Zhang X.H. and Zhu P.H.* (1998) Absence of detubulation in frog twitch muscle fibers exposed to protein kinase C activator.  Acta Physiol.Sinica. 50:213-216.

(14)          Zhang X.H. and Zhu.P.H.* (1997) Structure and pharmacology of ryanodine receptors.  Prog. Physiol. Sinica. 28:224-228. (review in Chinese).

(15) Zhang X.H. and Zhu P.H* (1996) Cyclic ADP-ribose and its calcium mobilizing function.  Prog. Biochem. Biophys. Sinica. 23:134-137 (review in Chinese).

 

ATTENDED SCIENTIFIC CONFERENCES

July 2007                  Gordon Conference on “The Inhibition in CNS”, Colby College, Maine, USA (oral report and poster presenter)

June 2005                  Gordon Conference on “Neural Circuits and Plasticity”, Salve Regina University, Rhode Island, USA (poster presenter)

June 2005                   Annual Meeting of HFSP Awardees, National Institutes of Health, Bethesda, Maryland, USA (oral report)

July 2004                      Shanghai-Toronto Symposium on Molecular Neuroscience, Institute of Neuroscience, Shanghai, China (oral report)

July 2003                    Annual Meeting of HFSP Awardees, Robison College, University of Cambridge, U.K (oral report)

February r 2003          Bio-X Life Science Research Center, College of Life Science and Biotechnology, Shanghai Jiao-Tong University, China (invited lecture)

November 2001          Neuroscience Retreat, Neurobiology Division, Department of Molecular and Cell Biology, University of California at Berkeley, USA (oral report)

 

Ad hoc REVIEWER OF JOURNALS

Journal of Neuroscience

Acta Physiologica Sinica (2003-  )