Increasing the dose of α 2B interferon therapy in

Increase of α 2B interferon dose in the treatment of chronic hepatitis B clinical observation
In accompanied by elevated serum transaminases and viral replication in chronic hepatitis B has better curative effect, is the preferred one of the drugs; before treatment in the patients with HBVDNA, ALT level and sex were predictive of response to interferon therapy [3J main factors, and the adverse effects of interferon, to achieve better case selection is very important effect.
Currently recommended 5MU dose, treatment for 6 months as appropriate, can prolong the period to 1 years, only the interferon treatment of chronic hepatitis by increasing the dosage appropriately contribute to improve the curative effect.
This group of cases respectively using a 2B interferon 6MU and 3MU, the total effective rate of treatment group, HBeAg conversion rate, ALT recovery than the control group; the incidence of adverse reactions is slightly higher, but no significant difference between ordinary; only IFN treatment of decompensated hepatitis B liver cirrhosis, hepatic decompensation occurs when the rate of < 1% laps, the group selection without cirrhosis cases, so no hepatic decompensation.
The results showed that: only one 2B interferon 6MU on chronic hepatitis b curative effect is remarkable, and the patients have good tolerance, that the use of only one 2B interferon 6MU therapy for chronic hepatitis B is feasible.
Ma Weimin think interferon 5MU group and 10MU group had no significant difference in efficacy between Ot, 2b interferon 6MU is superior to the 5MU and its long term efficacy to continue observing summary.
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Increasing the dose of α 2B interferon therapy in