我们热爱生命科学!-生物行

Jun Yang,Ph.D.(2)

时间:2011-12-01 08:44来源:University of Utah 作者:Jun Yang 点击: 509次
Publications:
1. Yang J and Zoeller RT. (2002) Differential display identifies neuroendocrine-specific protein-A (NSP-A) as an ethanol-responsive gene in the fetal rat brain. Brain Res Dev Brain Res, 138: 117 -133.
2. Yang J, Liu X, Yue G, Adamian M, Bulgakov O and Li T. (2002) Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet. J Cell boil, 159: 431 -440.
3. Hong D, Pawlyk B, Sokolov M, Strissel KJ, Arshavsky VY, Yang J, Tulloch B, Wright AF and Li T. (2003) RPGR isoforms in photoreceptor connecting cilia and the transitional zone of motile cilia. Invest Ophthalmol Vis Sci, 44: 2413 – 2421.
4. Liu X, Bulgakov O, Wen X, Woodruff ML, Pawlyk B, Yang J, Fain GL, Sandberg MA, Makino CL and Li T. (2004) AIPL1, the protein that is defective in Leber congenital amaurosis, is essential for the biosynthesis of retinal rod cGMP phosphodiesterase. Proc Natl Acad Sci USA, 101: 13903 -13908.
5. Yang J and Li T. (2005) The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos. Exp Cell Res, 309: 379 -389.
6. Yang J, Gao J, Adamian M, Wen X, Pawlyk B, Zhang L, Sanderson MJ, Zuo J, Makino CL and Li T. (2005) The ciliary rootlet maintains long-term stability of the sensory cilia. Mol Cell Biol, 25: 4129 – 4137.
7. Yang J, Adamian M and Li T. (2006) Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells. Mol Biol Cell, 17: 1033 – 1040.
8. Yang J and Li T. (2006) Rootletin. Exp Eye Res, 83: 1- 2.
9. Yang J, Pawlyk B, Wen X, Adamian M, Soloviev M, Michaud N, Zhao Y, Sandberg MA, Makino CL and Li T. (2007) Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals. Hum Mol Genet, 16: 1017 – 1029.
10. Yang J, Liu X, Zhao Y, Adamian M, Pawlyk B, Sun X, McMillan DR, Liberman MC and Li T. (2010) Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss. PLoS Genet, 6: e10000955.
11. Zou JH, Luo L, Shen Z, Choido V, Ambati BK, Hauswirth WW and Yang J. (2011) Whirlin replacement restores the formation of the USH2 protein complex in whirlin knockout photoreceptors. Invest Ophthalmol Vis Sci, 52: 2343 – 2351.
12. Yang J, Wang L, Song H and Sokolov M. (2012) Current understanding of Usher syndrome type II. Frontiers in Bioscience, 17: 1165 – 1183.
13. Wang L, Zou JH, Shen Z, Song E and Yang J. (in press) Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II. Hum Mol Genet.
14. Yang J. (in press) Usher syndrome: genes, proteins, models, molecular mechanisms, and therapies. In Sadaf Naz (Ed.), Hearing loss. Rijeka: Intech.
 
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