我们热爱生命科学!-生物行

Jian Yang (杨建)  Ph.D.(2)

时间:2008-07-23 11:22来源:Columbia 作者:bioguider 点击: 561次
  • Michailidis, Y., Zhang, Y., and Yang, J. (2007).  The lipid connection - Regulation of voltage-gated Ca2+ channels by phosphoinositides.  Pflugers Ach. 455, 147-155.  (Review)
  • He., L-l., Zhang, Y.,  Chen, Y-h., Fitzmaurice, A., and Yang, J. (2007).  Functional modularity of the b subunit of voltage-gated Ca2+ channels. Biophysical Journal 93, 834-845.
  • Zhen, X-G*., Xie, C*., Yamada, Y., Zhang, Y., Doyle, C., and Yang, J. (2006).  A single amino acid mutation slows rundown of voltage-gated calcium channels.  FEBS Letters  580, 5733-5738.
  • Zhen, X-G*., Xie, C*., Orenstein, E., and Yang, J.  (2005).  Functional architecture of the inner pore of a voltage-gated Ca2+ channel.  J. Gen. Physiol. 126, 193-204.

  • Xie, C*., Zhen, X-G*., and Yang, J. (2005).  Localization of the activation gate of a voltage-gated Ca2+ channel.  J. Gen. Physiol.  126, 205-212.

  • Gamper, N., Reznikov, V., Yamada, Y., Yang, J., and Shapiro, M.S. (2004).  PIP2 signals underlie receptor-specific Gq/11-mediated modulation of N-type Ca2+ channels.  J. Neurosci.  24, 10980-10992.

  • Chen, Y-h., Li, M-h., Zhang, Y.,  He., L-l., Yamada, Y., Fitzmaurice, A., Shen, Y., Zhang, H., Tong, L., and Yang, J. (2004).  Structural basis of the a1-b interaction of voltage-gated Ca2+ channels.  Nature 429, 675-680.
  • Jun, X., Zhen, X-G., and Yang, J. (2003).  Localization of PIP2 activation gate in inward rectifier K+ channels.  Nature Neurosci. 6, 811-818.
  • Wu, L., Bauer, C., Zhen, X-G., Xie, C., and Yang, J. (2002).  Dual regulation of voltage-gated calcium channels by PIP2.  Nature 419, 947-952.
  • Lopes, C.M.B., Zhang, H., Rohacs, T., Jin, T.,  Yang, J., and Logothetis, D.E. (2002).  Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies.  Neuron 34, 933-944.
  • Lu, T., Wu, L., Xiao, J., and Yang, J. (2001).  Permeant ion-dependent changes in gating of Kir2.1 inward rectifier potassium channels.  J. Gen. Physiol. 118, 509-521.
  • Lu, T., Ting, A.Y., Mainland, J., Jan, L.Y., Schultz, P.G., and Yang, J. (2001).  Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter.  Nature Neurosci. 4, 239-246.
  • Lu, T., Zhu, Y-G., and Yang, J. (1999).  Cytoplasmic amino and carboxyl domains form a wide internal vestibule in an inwardly rectifying K+ channel.  Proc. Natl. Acad. Sci. 96, 9926-9931.
  • Lu, T., Zhang, X-M., Nguyen, B., and Yang, J. (1999).  Architecture of a K+ channel inner pore revealed by stoichiometric covalent modification.  Neuron 22, 571-580.
  • Yang, J., Jan, Y.N., and Jan, L.Y. (1997).  Stabilization of ion selectivity filter by pore loop ion-pairs in an inward rectifier K+ channel.  Proc. Natl. Acad. Sci. 94, 1568-1572.
  • Fakler, B., Schultz, J., Yang, J., Schulte, U., Brandel, U., Zenner, H.P., Jan, L.Y., and Ruppersberg, J.P. (1996).  Identification of a titratable lysine residue that determines sensitivity of kidney potassium channels (ROMK) to intracellular pH.  EMBO J. 15, 4093-4099.
  • Yang, J., Jan, Y.N., and Jan, L.Y. (1995a).  Determination of the subunit stoichiometry of an inwardly rectifying K+ channel.  Neuron 15, 1441-1447.
  • Yang, J., Jan, Y.N., and Jan, L.Y. (1995b).  Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel.  Neuron 14, 1047-1054.
  • Ellinor, P. T., Yang, J., Sather, W.A., Zhang, J.F., and Tsien, R.W. (1995).  Ca2+ channel selectivity at a single locus for high-affinity Ca2+ interactions.  Neuron 15, 1121-1132.
  • Sather, W. A., Yang, J., and Tsien, R.W. (1994).  Structural basis of ion channel permeation and selectivity.  Curr. Opinion in Neurobiol. 4, 313-323.  (Review)
  • Yang, J., Ellinor, P.T., Sather, W.A., Zhang, J.F., and Tsien, R.W. (1993).  Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels.  Nature 386, 158-161.
  • Yang, J., and Tsien, R.W. (1993). Enhancement of N- and L-type calcium channel currents by protein kinase C in frog sympathetic neurons.  Neuron 10, 127-136.
  • Yang, J., Mathie, A., and Hille, B. (1992). 5-HT3 receptor channels in dissociated rat superior cervical ganglion neurons.  J. Physiol. 448, 237-256.
  • Yang, J. (1990).  Ion permeation through 5-HT-gated channels in neuroblastoma N18 cells. J. Gen. Physiol. 96, 1177-1198.
  • Yang, J., and Roper, S.D. (1987).  Dye-coupling in taste buds in the mudpuppy, Necturus maculosus.  J. Neurosci. 7, 3561-3565.

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