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SAMUEL M. SCHACHER Ph.D.

时间:2008-09-01 04:38来源:本站原创 作者:bioguider 点击: 338次

SAMUEL M. SCHACHER

 

ACADEMIC TRAINING:

1971                B.S. in Applied Biology, Columbia University School of Engineering, New York, NY

1973                Physiology Course, Marine Biological Laboratories, Woods Hole, MA

1974,1976       M.A., Ph.D. in Biology, Department of Biological Sciences, Columbia University Graduate School of Arts and Sciences, New York, NY

Thesis:            Synaptic activity of vertebrate photoreceptors: A peroxidase uptake study in isolated frog retinas.

Sponsor:          Dr. Eric Holtzman

 

POSTDOCTORAL TRAINING:

1976-1978       Department of Physiology, Division of Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, NY.

Sponsor:          Dr. Eric R. Kandel

 

PROFESSIONAL SOCIETIES:

American Association for the Advancement of Science

New York Academy of Sciences

Society for Neuroscience

 

ACADEMIC APPOINTMENTS:

July 2007-       Professor of Neuroscience (in Psychiatry), Department of Neuroscience Columbia University College of Physicians and Surgeons

July 1997-       Professor of Neurobiology and Behavior (in Psychiatry and in Anatomy and Cell Biology), Columbia University College of Physicians and Surgeons

1989-1997       Associate Professor of Neurobiology and Behavior (in Psychiatry and in Anatomy and Cell Biology), Columbia University College of Physicians and Surgeons

1985-1989       Assistant Professor of Anatomy and Cell Biology (in Psychiatry and in the Center for Neurobiology and Behavior), Columbia University, College of Physicians and Surgeons

1980-1985       Assistant Professor of Anatomy and Psychiatry, Division of Neurobiology and Behavior, Columbia University, College of Physicians and Surgeons

1978-1980       Staff Associate, Department of Neurology, Division of Neurobiology and Behavior, Columbia University College of Physicians and Surgeons

 

HONORS:

1985-1987       McKnight Developmental Neuroscience Fellow

1975                John S. Newberry Prize, Columbia University

1973                Charles Heubschman Prize, Columbia University

 

FELLOWSHIPS:

1976-1978       National Research Service Award (NIH)

1967-1971       New York State Regents Scholarship

 

PROFESSIONAL SOCIETIES:

American Association for the Advancement of Science

New York Academy of Sciences

Sigma Xi

Society for Neuroscience

 

UNIVERSITY & OTHER PROFESSIONAL ACTIVITIES:

Coordinated Admissions Committee for Graduate Program Columbia Health Sciences

NINCDS Study Section (Neuro B II), 1990-1994

NINDS Fellowship Study Section (F03A), 2003-2007

Ad hoc Reviewer for NSF

Reviewer for J. Neuroscience, J. Neurobiology, J. Neurophysiology, J. Neurochemistry and Neuron

 

Lectures and Seminars:

United States: Albert Einstein-Yeshiva University School of Medicine, AT & T Bell Laboratories, Case Western Reserve University School of Medicine, City University of New York, Colorado State University, Cornell School of Medicine (2X), Emory University School of Medicine, Iowa State University, Mt. Sinai School of Medicine (2x), New York Medical College, New York University, Roche Institute of Molecular Biology, Rutgets – Piscataway, SUNY (Albany, Buffalo, Downstate, Stony Brook), University of California-San Diego, UMDNJ – Newark, University of Iowa, University of Missouri-Columbia, University of Pennsylvania (2X), University of Pittsburgh, University of Tennessee, Vanderbilt University, Yale University (2X).

Foreign:  Bar Ilan University, Israel (2X); Ben Gurion University, Israel; Dahlem Conference, Berlin; Technion University, Israel; Hebrew University, Israel (3X); McGill University, Canada; Montreal University, Canada; University of Calgary Health Sciences, Canada; University of Edinburgh, UK; Weizmann Institute, Israel (2X), Tel Aviv University School of Medicine, Israel.

 

PUBLICATIONS:

1.   Schacher, S., Holtzman, E. and Ebrey, T. (1973).  Cytochemical studies of peroxidase uptake and other features of frog retinal photoreceptor cells.  J. Histochem. Cytochem., 21: 419-420.

2.  Schacher, S., Holtzman, E. and Hood, D. (1974).  Uptake of horseradish peroxidase by frog photoreceptor synapses in the dark and the light. Nature, 249: 261-263.

3.  Schacher, S., Holtzman, E. and Hood, D. (1976).  Synaptic activity of frog retinal photoreceptors: A peroxidase uptake study.  J. Cell Biol., 70: 178-192.

4.  Holtzman, E., Schacher, S., Evans, J. and Teichberg, S. (1977).  Origin  and fate of the membranes of secretion granules and synaptic  vesicles; membrane circulation in neurons, gland cells and retinal  photoreceptors.  In Cell Surface Review, Vol. 4, eds.:  G.L. Poste and G. Nicholson.  Amsterdam: Elsevier North-Holland, pp. 165-246.

5.  Schacher, S., Kandel, E.R. and Woolley, R. (1979).  Development of neurons in the abdominal ganglion of Aplysia californica. I. Axosomatic synaptic contacts. Dev. Biol. , 71: 163-175.

6.  Schacher, S., Kandel, E.R. and Woolley, R. (1979).  Development of neurons in the abdominal ganglion of Aplysia californica. II. Nonneural support cells.  Dev. Biol., 71: 176-190.

7.   Kandel, E.R., Kriegstein, A. and Schacher, S. (1980).  Development of the central nervous system of Aplysia in terms of the differentiation of its specific identifiable cells.  Neuroscience, 5: 2033-2063.

8.    Schacher, S. (1981).  The role of support cells in the growth and differentiation of neurons in the abdominal ganglion of Aplysia.  J. Exp. Biol., 95: 205-214.

9.   Schacher, S. (1982).  Cellular interactions in the development of neurons in the abdominal ganglion of Aplysia. Neurosci. Res. Prog. Bull., 20: 870-877.

10.  Schacher, S., and Proshansky, E. (1983).  Neurite regeneration by Aplysia   neurons in dissociated cell culture:  Modulation by Aplysia hemolymph and the presence of the initial axonal segment.  J. Neurosci., 3: 2403-2413.

11.  Camardo, J., Proshansky, E. and Schacher, S. (1983).  Identified Aplysia neurons form specific chemical synapses in culture.  J. Neurosci., 3: 2614-2620.

12.  Schacher, S. (1985).  Differential synapse formation and neurite outgrowth at two branches of the metacerebral cell of Aplysia in dissociated cell culture. J. Neurosci., 5: 2851-2856.

13.  Schacher, S., Rayport, S.G and Ambron, R.T. (1985).  Giant Aplysia neuron R2 reliably forms chemical connections in vitro.  J. Neurosci., 5: 2851-2856.

     

14.  Ambron, R.T., Den, H. and Schacher, S. (1985).  Synaptogenesis by single identified neurons in vitr Contribution of rapidly transported and newly synthesized proteins. J. Neurosci., 5: 2857-2865.

      

15.  Ambron, R.T., Schacher, S. and Rayport, S.G. (1985).  Proteins rapidly transported to the synapse of a single identified neuron of Aplysia.  J. Neurosci., 5: 2866-2873.

16.  Castellucci, V.F., Schacher, S., Montarolo, P.G., Mackey, S., Glanzman, D.L., Hawkins, R.H., Abrams, T.W., Goelet, P. and Kandel, E.R. (1985).  Convergence of small molecule and peptide transmitters on a common molecular cascade.  In Progress in Brain Research, Vol 68, eds.:  T. Hokfelt, K. Fuxe and P. Pernow.   Amsterdam: Elsevier North-Holland, pp. 83-102.    

17.  Rayport, S.G. and Schacher, S. (1986).  Synaptic plasticity in vitr Cell culture of identified Aplysia neurons mediating short-term habituation and sensitization. J. Neurosci., 6: 759-763.

18.  Belardetti, F., Schacher, S. and Siegelbaum, S.A. (1986).  Action potentials, macroscopic and single channel currents recorded from the growth cones of Aplysia neurons in culture.  J. Physiol. (London), 374: 289-313.

19.  Goelet, P., Castellucci, V.F., Schacher, S. and Kandel, E.R. (1986).  The long and the short of long-term memory--a molecular framework.  Nature, 322: 419-422.

20.  Belardetti, F., Schacher, S., Kandel, E.R. and Siegelbaum, S.A. (1986).  The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents.  Proc. Natl. Acad. Sci. USA, 83: 7094-7098.

21.  Hochner, B., Klein, M., Schacher, S. and Kandel, E.R. (1986a).  Action potential duration and the modulation of transmitter release from the sensory neurons of Aplysia in presynaptic facilitation and behavioral sensitization.  Proc. Natl. Acad. Sci. USA, 83: 8410-8414. (责任编辑:泉水)
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