Single-Channel Recording
Second Edition
edited by
Bert Sakmann
Max-Planck-Institut für Medizinische Forschung, Heidelberg, Germany
Erwin Neher
Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Germany
Editorial Reviews
From Book News, Inc.
The single-channel recording technique has reached the status of a routine method, and the view that conductance changes in biological membranes are caused by the openings and closings of ion channels is now almost universally accepted. This volume contains 22 chapters in four parts: introduction to patch clamping; methods; analysis; and "classics." There is also an appendix on improved patch-clamp techniques for high-resolution current recording from cells and cell- free membrane patches. The first edition was published in 1983. Annotation copyright Book News, Inc. Portland, Or.
Book Info
Max-Planck-Institute, Germany. Second edition of a reference of techniques in the use of channels and pipettes in the patch clamping process. Previous edition 1983. For researchers in membranes and cell transport. 28 contributors, 4 U.S.
Book Description
From reviews of the First Edition: A landmark in the field of membrane biophysics.--Science A first-class laboratory guide...an indispensable reference.--Neuroscience Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping.