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APE v2.0.46

软件类型:国外软件 授权方式:公开 界面语言:英语 软件大小:5MB 文件类型:.exe 运行环境:Win9x/NT/2000/XP/ 软件等级:★★★★★ 发布时间:2013-03-17 官方网址:http://biologylabs.utah.edu/jo 演示网址:http://biologylabs.utah.edu/jorgensen/wayned/ape/ 下载次数:
软件介绍

 

  • Runs in Windows (XP, Vista and 7) and Mac (OS X v10.5 and above)
  • Highlights restriction sites in the editing window
  • Accurately reflects Dam/Dcm blocking of enzyme sites
  • Highlights text using pre-defined and custom feature libraries
  • Shows translation, Tm, %GC, ORF of selected DNA in real-time
  • Reads DNA Strider, Fasta, Genbank and EMBL files
  • Saves files as DNA Strider-compatible or Genbank file format
  • Highlights and draws graphic maps using feature annotations from genbank and embl files
  • Directly BLASTs selected sequence at NCBI or wormbase

 

  • Text map shows DNA sequence, translation, and features as text-based graphics

 

  • Creates graphic restriction maps- linear or circular with features indicated
  • Connects graphic and text features with hyperlink double click
  • Saves graphics as encapsulated postscript or scalable vector graphics
  • Copy and save graphics as Windows metafiles (MS Windows only)

 

  • Virtual restriction digest
  • Draws pre-defined and user-defined DNA ladders
  • Connects bands to text by double-click

 

  • Reads ABI sequencing trace files
  • Sequences in ABI traces can be aligned directly to a reference sequence, with the alignment hyperlinked back to te trace.

 

  • Selects sites matching multiple criteria (union/intersection- cut frequency, site type) in all open windows
  • Selects sites that cut more often in one sequence than another (for snip-SNP detection or diagnostic digests)
  • Has user defined enzyme grouping to distiguish eg. enzymes currently in stock.
  • Allows users to define new enzymes by name and recognition site
  • Imports DNA Strider format files (simple enzyme, site lists) available from REBASE

Other Features:

 

  • Most analysis windows are hyperlinked to their corresponding sequences, including:
    • Graphic Maps
    • Text maps
    • Virtual Digests
    • Alignments (including ABI sequences)
    • Silent Sites
    • Translation
    • Primer Find
  • Uses custom feature definition libraries, which allow:
    • Quick annotation of sequence
    • Quick searching and highlighting of all available primers that you (or others) have that hybridize to a sequence
    • Sequence to be annotated and visualized in multiple ways quickly and efficiently
    • Graphic maps that show primer binding sites and all interesting sequence features
  • Translates sequences with optional DNA alignment
  • Finds potential primers matching user criteria (length, Tm, %GC, self/other complementarity)
  • Aligns two DNA sequences (or any combination of sequence and ABI trace), with the alignment hyperlinked to the original sequence
  • Finds translationally silent restriction sites
  • Draws graphic ORF maps
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