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APOB XbaI Polymorphism is a genetic variation in the APOB gene, which encodes apolipoprotein B, a primary component of low-density lipoprotein (LDL) particles. This polymorphism involves a single nucleotide change at the XbaI restriction site, leading to either a 230 bp or a 160 bp fragment after digestion with the XbaI enzyme. The presence of this polymorphism can influence lipid metabolism and has been studied for its association with various lipid disorders.

Understanding the APOB XbaI polymorphism is crucial for advancing our knowledge of lipid metabolism and its role in cardiovascular diseases. This polymorphism serves as a genetic marker that can help in the diagnosis and management of lipid-related conditions.

Reference: Boerwinkle, E., S.S.Lee, R. Butler, VN Schumaker, and L. Chan, 1990. Rapid typing of apolipoprotein B DNA polymorphisms by DNA amplification. Athero 81:225-232.