“This newly devised cell culture system enables a new paradigm in stem cell research,” says Chemical and Biological Engineering Professor and MRSEC Director Juan de Pablo. “Ultimately, we hope to use liquid crystalline materials to transmit desired sets of physical and chemical cues to stem cells so as to control their differentiation, as well as report back specific responses of the cells or tissue. This research is also significant as an example of our unique effort to integrate advanced materials engineering and embryonic stem cell research, an effort that will help accelerate the rate at which the benefits of stem-cell based therapies are brought to society.” In addition to Palecek and de Pablo, authors of the paper include former post-doctoral researcher Nathan Lockwood, Graduate Student Jeff Mohr, Researcher Lin Ji, School of Veterinary Medicine (Ophthalmology) and Biomedical Engineering Professor Christopher Murphy, and Chemical and Biological Engineering Professor Nicholas Abbott. (责任编辑:泉水) |