A small protein in the brain that has only recently been discovered and, paradoxically, induces both profound wakefulness and a less anxious state, may represent a novel target for the treatment of psychotic behavior and schizophrenia, acc...

A recent volume of the Annals of the New York Academy of Sciences takes a closer look at how music evolved and how we respond to it. Contributors to the volume believe that animals such as birds, dolphins and whales make sounds analogous t...

Abbottannounced today results of two analyses from a major Phase III study ofHUMIRA(R) (adalimumab) in ankylosing spondylitis (AS). The first analysisdemonstrates the ability of HUMIRA to maintain the reduction of signs andsymptoms in...

Surgery to repair aortic aneurysms often comes with a high price: neurological deficits, but research points to a possible defense against spinal cord injury during aortic surgery. The paper by Roseborough et al., "The mitochondrial K-...

Dr. Tallie Z. Baram, a UC Irvine School of Medicine neurologist and one of the world's top epilepsy researchers, has received a Senator Jacob Javits Award in the Neurosciences, the nation's most prestigious prize for cutting-edge research...

Neuroscientists have proposed a simple explanation for the pleasure of grasping a concept: The brain is getting its fix. The "click" of comprehension triggers a biochemical cascade that rewards the brain with a shot of natural opium-li...

In this week's Journal, Assanah et al. tested the potential of glial progenitor cells as cells of origin for malignant glial tumors. The authors injected adult rat brain white matter with a retrovirus driving expression of green fluorescen...

Mammalian ovulation is the culmination of a complex neurohormonal signaling pathway. Gonadotropin-releasing hormone (GnRH) is normally under tonic negative feedback control, but estrogen triggers a GnRH/luteinizing hormone (LH) surge that...

Switching between Fear and AttractionStephanie Moriceau, Donald A. Wilson, Seymour Levine, and Regina M. Sullivan Neonatal rats learn rapidly to use odors to identify their mother. Pups are aided in this task by a boost in odor-preference...

The synaptic vesicle protein synaptobrevin is an essential component of the vesicle release machinery along with its plasma membrane partners (syntaxin and SNAP-25), although in the absence of synaptobrevin release it is not completely eli...